AIM: to develop an ELM (Engineered Living Material) biocontainment system where engineered bacteria can only survive in specific microenvironments created within materials.
STRATEGY:
• Genetic Engineering: design survival switches in bacteria (models: E. coli and L. plantarum).
• Material Design: develop materials that induce survival conditions for these bacteria.
• Integration: combine bacteria and materials to demonstrate functional biocontainment in a simulated real-world scenario.
This innovative approach merges biomaterials and synthetic biology to create safer and more versatile applications for ELMs.
Team
Principle Investigator
Head, Functionalized Coatings
Institute of Functional Interfaces
Karlsruhe Institute of Technology
PhD Student
Functionalized Coatings
Institute of Functional Interfaces
Karlsruhe Institute of Technology
Co – Investigator
Co-Director, Institute of Functional Interfaces
Karlsruhe Institute of Technology
Director, Biointerfaces Institute
University of Michigan
Principle Investigator
Head, Bioprommable Materials
INM – Leibniz Institute for New Materials, Saarbrücken
PhD Student
Bioprommable Materials
INM – Leibniz Institute for New Materials, Saarbrücken